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Predictors of mortality after acute stroke a prospective hospital based study
Insights
Acute stroke mortality was 17.4% within 14 days. Key predictors of death include hypertension, brain infarction, hemorrhagic stroke, and atrial fibrillation, highlighting the need for risk factor control.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Stroke is a leading global cause of death, with high mortality rates in acute ischemic stroke patients.
- Identifying predictors of mortality is crucial for improving patient outcomes.
- This study investigated factors influencing mortality following acute stroke.
Purpose of the Study:
- To identify predictors of mortality in patients with acute stroke.
- To analyze the impact of various clinical and demographic variables on stroke outcomes.
- To inform strategies for stroke prevention and management.
Main Methods:
- Prospective study of 149 acute stroke patients at Hospital Muzaffarabad, Azad Kashmir.
- Mortality assessed using Modified Ranking Scale (mRS) and Glasgow Coma Scale (GCS).
- Included clinical evaluation, neurological assessment, laboratory tests, brain CT, and 14-day follow-up.
Main Results:
- Hospital mortality rate was 17.4% within 14 days.
- Significant predictors of mortality included hypertension, brain infarction, hemorrhagic stroke, atrial fibrillation, high mRS, and low GCS score on admission.
- Age and gender did not significantly impact mortality.
Conclusions:
- Acute stroke resulted in a 17.4% mortality rate at 14 days in this cohort.
- Effective prevention and control of identified risk factors are essential for reducing stroke-related mortality.
Background:
The stroke is third leading cause of death in world and 10% of patients with an acute ischemic stroke die within 30 days. Various clinical variables have been implicated as predictors of final outcome of acute stroke. The study was aimed to identify predictors of mortality after an acute stroke.
Material And Methods:
This prospective study included 149 consecutive patients of acute Hospital Muzaffarabad, Azad Kashmir. The outcome as mortality measures used were Modified Ranking Scale (mRS) and Glasgow Coma Scale (GCS). Examination included clinical, neurological evaluation, laboratory tests, and brain CT. The follow-ups at 14 days were done for all patients.
Results:
Hospital mortality was 17.4% (26/149) within 14 days. Age and gender had no impact on mortality. Hypertension (p = 0.008), smoking (p = 0.056)), brain infarction (p = < 0.001), hemorrhagic stroke (p = < 0.001), diabetes (p = 0.292), atrial fibrillation (p < 0.001), high mRS (p < 0.001), low GCS score (p < 0.001), on admission were important predictors of mortality.
Conclusions:
We report 17.4% mortality at 14 days. Mortality associated with acute stroke needs prevention and control of risk factors.
