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Burning mouth syndrome: patch test results from a large case series
Journal of Cutaneous Medicine and Surgery
|May 8, 2014
Summary
Patch testing is a valuable diagnostic tool for burning mouth syndrome (BMS), revealing potential contact allergies in a majority of patients. This allergy may be a key factor in developing BMS.
Area of Science:
- Oral Medicine
- Dermatology
- Allergology
Background:
- Burning mouth syndrome (BMS) presents as oral burning without mucosal changes, posing diagnostic and therapeutic challenges.
- Etiological theories for BMS include contact allergy, necessitating further investigation.
Purpose of the Study:
- To evaluate the clinical usefulness of patch testing in diagnosing burning mouth syndrome.
- To identify potential allergens contributing to BMS.
Main Methods:
- Retrospective chart review of 142 patients diagnosed with BMS.
- Analysis of patch testing results performed between January 2008 and July 2012.
Main Results:
- 67% of tested BMS patients (89/132) showed positive allergic patch test reactions.
- 74% of positive reactions were considered clinically relevant.
- Common allergens included nickel sulfate, gallates, fragrance mix, benzoyl peroxide, and cinnamic alcohol.
Conclusions:
- Contact allergy is a likely etiological factor in a significant subset of BMS patients.
- Patch testing is a clinically useful diagnostic method for investigating BMS.
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