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A PrP(C)-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor

Julia Hernandez-Rapp1, Séverine Martin-Lannerée2, Théo Z Hirsch2

  • 11] INSERM UMR-S1124, 75006 Paris France [2] Université Paris Descartes, Sorbonne Paris Cité, UMR-S1124, 75006 Paris France [3] Université Paris Sud 11, ED419 Biosigne, 91400 Orsay, France [4].

Scientific Reports
|May 10, 2014
PubMed
Summary

The cellular prion protein (PrP(C)) regulates GSK3β kinase activity in brain cells, influencing serotonin signaling and neurotransmission. This discovery sheds light on PrP(C)

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