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Updated: Apr 30, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
Published on: September 26, 2013
[Interleukin-17 as a therapeutic target in psoriasis]
1Consulta de Psoríase. Serviço de Dermatologia. Centro Hospitalar do Porto. Porto. Portugal. Unidade Multidisciplinar de Investigação Biomédica. Instituto de Ciências Biomédicas Abel Salazar. Universidade do Porto. Porto. Portugal.. tiagotorres2002@hotmail.com.
New drugs targeting Interleukin-17 (IL-17) show promise for treating psoriasis. These therapies focus on the immune pathways involved in this chronic inflammatory skin condition.
Area of Science:
- Immunology
- Dermatology
Context:
- Psoriasis is a prevalent chronic inflammatory disease.
- Understanding its immune-pathogenesis is advancing treatment options.
Purpose:
- To explore the role of Interleukin-17 (IL-17) in psoriasis.
- To evaluate IL-17 inhibitors as a therapeutic strategy.
Summary:
- Th17 cells and the cytokine IL-17A are key players in psoriasis pathogenesis.
- IL-17 is also expressed by innate immune cells in psoriatic lesions.
- IL-17 inhibitors are under development with promising preliminary results.
Impact:
- IL-17 inhibition offers a targeted approach to autoimmune diseases like psoriasis.
- These novel therapies may become alternatives to existing biologic agents.
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