Related Experiment Videos
[Thrombocyte-specific antigens/antibodies and their clinical importance]
C Mueller-Echardt1, V Kiefel, S Santoso
1Institut für Klinische Immunologie und Transfusionsmedizin, Justus-Liebig-Universität, Giessen, BRD.
Beitrage Zur Infusionstherapie = Contributions to Infusion Therapy
|January 1, 1989
Abstract:
This review updates our present state of knowledge with regard to platelet-specific alloantigens, i.e. Zwa/Zwb (PlAl/PlA2), Baka/Bakb, Koa/Kob, Yuka/Yukb (Penb/Pena), Bra/Brb, Nak, Sib, and summarizes relevant immunogenetical and biochemical data. The impact of corresponding platelet-specific antibodies in clinical conditions such as neonatal alloimmune thrombocytopenia, posttransfusion purpura, and the refractory state of platelet transfusions is reviewed with particular emphasis on our own case material.