Related Experiment Video
Updated: Apr 29, 2026

Generation of Marked and Markerless Mutants in Model Cyanobacterial Species
Published on: May 29, 2016
A new lyngbyatoxin from the Hawaiian cyanobacterium Moorea producens
Weina Jiang1, Wei Zhou2, Hajime Uchida3
1Department of Ocean Sciences, Tokyo University of Marine Science and Technology, Tokyo 108-8477, Japan. jwnkouina@gmail.com.
Abstract:
Lyngbyatoxin A from the marine cyanobacterium Moorea producens (formerly Lyngbya majuscula) is known as the causative agent of "swimmer's itch" with its highly inflammatory effect. A new toxic compound was isolated along with lyngbyatoxin A from an ethyl acetate extract of M. producens collected from Hawaii. Analyses of HR-ESI-MS and NMR spectroscopies revealed the isolated compound had the same planar structure with that of lyngbyatoxin A. The results of optical rotation and CD spectra indicated that the compound was a new lyngbyatoxin A derivative, 12-epi-lyngbyatoxin A (1). While 12-epi-lyngbyatoxin A showed comparable toxicities with lyngbyatoxin A in cytotoxicity and crustacean lethality tests, it showed more than 100 times lower affinity for protein kinase Cδ (PKCδ) using the PKCδ-C1B peptide when compared to lyngbyatoxin A.
More Related Videos
Related Concept Videos
Bacterial Toxins
Bacterial Phylum Cyanobacteria
Anoxygenic Phototrophic Bacteria
Anoxygenic Photosynthesis
Gene Regulation in Microbial Communities: Quorum Sensing
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

