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Related Experiment Video

Updated: Apr 29, 2026

Metacarpal Small Incision for Carpal Tunnel Syndrome
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Plexiform neurofibroma presenting as wrist synovitis: a case report.

B Altman, L K Ruby

    Orthopedics
    |May 17, 2014
    PubMed
    Summary

    This case report details a rare instance of plexiform neurofibroma in the wrist, initially mistaken for juvenile rheumatoid arthritis due to similar clinical and imaging findings. Biopsy confirmed the correct diagnosis, highlighting a unique presentation in medical literature.

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    Wrist arthrography revisited.

    Orthopedics·2014
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    Wrist arthrodesis: an alternative technique.

    Orthopedics·1998
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    Ulnar styloid impaction syndrome.

    The Journal of hand surgery·1997
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    Open vs endoscopic carpal tunnel release.

    Orthopedics·1996
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    Emotional processing and outcome of imaginal flooding therapy in Vietnam veterans with chronic posttraumatic stress disorder.

    Comprehensive psychiatry·1996
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    Emotional processing during eye movement desensitization and reprocessing therapy of Vietnam veterans with chronic posttraumatic stress disorder.

    Comprehensive psychiatry·1996

    Area of Science:

    • Orthopedic Surgery
    • Rheumatology
    • Oncology

    Background:

    • Presents a unique case of plexiform neurofibroma of the wrist.
    • The mass mimicked clinical and radiological features of juvenile rheumatoid arthritis.
    • Highlights the importance of biopsy in differential diagnosis.

    Discussion:

    • Discusses the challenges in differentiating benign neurofibromas from inflammatory arthropathies.
    • Emphasizes the rarity of plexiform neurofibroma presenting as a diffuse wrist mass.
    • Explores potential diagnostic pitfalls in rheumatological and orthopedic evaluations.

    Key Insights:

    • Plexiform neurofibroma can present as a diffuse wrist mass.
    • Radiological and clinical findings can be misleading, mimicking inflammatory conditions like juvenile rheumatoid arthritis.
    • Histopathological examination is crucial for definitive diagnosis.

    Outlook:

    • Suggests increased vigilance for neurofibromas in wrist masses with atypical presentations.
    • Recommends considering soft tissue tumors in the differential diagnosis of wrist swelling.
    • Further research into the specific presentation of plexiform neurofibromas in the wrist may be warranted.

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