[Evaluation of the functional state of the complement and fibrinolysis systems]

The blood complement and fibrinolytic activities were examined in 89 patients with Stages III-IV pulmonary and gastric carcinomas. The studies have revealed that local hypoxia of the upper limb as a test stimulant evokes similar reactions of the examined systems, which evidences their functional relationship. Three reaction types of the complement and fibrinolytic systems were singled out: increased, decreased, or unchanged activities. These reactions qualitatively and quantitatively differ in normal subjects and patients with the disseminated forms of pulmonary and gastric carcinomas. The results permit a conclusion that use of a local hypoxia functional test makes the measurements of the blood complement and fibrinolytic activities more informative and permits a judgement on the reserve potentials of these systems.