Related Experiment Video
Updated: Apr 29, 2026

15:07
VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
Published on: December 28, 2015
26.3K
Hairy cell leukemia accompanied by Evans syndrome
Shigeyuki Ebara1, Mizuho Kagosima, Mikio Marumo
1Department of Internal Medicine, Kobe Tokushukai Hospital.
Summary
We describe a rare case of Western type hairy cell leukemia (HCL) in Japan, often missed due to preparation methods and pancytopenia. The patient presented with Evans syndrome, indicating complex immune dysregulation in HCL.
Area of Science:
- Hematology
- Oncology
- Immunology
Background:
- Western type hairy cell leukemia (HCL) is exceptionally rare in Japan.
- Diagnostic challenges include pancytopenia and loss of typical cell morphology with conventional preparation methods.
- HCL can be associated with immune dysregulation, including autoantibody production.
More Related Videos
Related Concept Videos
Rous Sarcoma Virus (RSV) and Cancer
5.2K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.2K
Rous Sarcoma Virus (RSV) and Cancer
5.0K
5.0K

