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Using chromatography in downstream processing.

C Becker1

  • 1Pharmacia LKB Biotechnology.

Australian Journal of Biotechnology
|January 1, 1989
PubMed
Summary
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This article provides an overview of process chromatography for downstream processing, covering component selection and process standards. It highlights Pharmacia LKB Biotechnology

Area of Science:

  • Biotechnology
  • Chemical Engineering

Background:

  • The series concludes by examining chromatography in downstream processing.
  • Process chromatography involves numerous complex parameters.
  • A broad overview is presented, encompassing component selection and process standards.

Purpose of the Study:

  • To provide a comprehensive overview of process chromatography for downstream applications.
  • To summarize key considerations for successful product purification using chromatography.
  • To leverage Pharmacia LKB Biotechnology's extensive experience in large-scale chromatographic processes.

Main Methods:

  • Review of process chromatography principles and applications.
  • Discussion of component selection for chromatographic systems.

Related Experiment Videos

  • Consideration of process standards in large-scale purification.

    • Main Results:

    • The article offers a broad overview of process chromatography, despite the complexity of the field.
    • Key factors for successful product purification have been identified.
    • Pharmacia LKB Biotechnology's 15+ years of experience inform the presented information.

    Conclusions:

    • Chromatography is a critical technique in downstream processing.
    • Successful implementation requires careful consideration of various parameters and standards.
    • Expertise in designing, developing, and running large-scale chromatographic processes is essential for efficient product purification.