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Published on: May 21, 2019
ZnO-supported Pd nanoparticle-catalyzed ligand- and additive-free cyanation of unactivated aryl halides using
Tanmay Chatterjee1, Raju Dey, Brindaban C Ranu
1Department of Organic Chemistry, Indian Association for the Cultivation of Science , Jadavpur, Kolkata-700032, India.
Abstract:
The use of a new ZnO-supported palladium(0) nanoparticle catalyst for the cyanation of aryl halides using a relatively benign cyanide source, K4[Fe(CN)6], is described. This catalyst has been applied for the efficient cyanation of a variety of functionalized aryl bromides and activated aryl chlorides. This process circumvents the need for an additive and a ligand for the reaction and offers the advantages of high product yields, low catalyst loading (0.2 mol % Pd), and recyclability of the catalyst.
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