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Updated: Apr 29, 2026

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Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea
Published on: January 24, 2018
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Concepts and misconceptions in corneal biomechanics.
1From the Department of Ophthalmology and Visual Science, Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, USA.
Journal of Cataract and Refractive Surgery
|May 27, 2014
Summary
This review clarifies biomechanical concepts for in vivo corneal assessment using air-puff deformation. It addresses misconceptions and discusses viscoelasticity
Area of Science:
- Ophthalmology
- Biomechanics
- Corneal Physiology
Background:
- Review of existing literature on corneal biomechanical assessment.
- Discussion of financial disclosures relevant to the research.
Purpose of the Study:
- To clarify biomechanical concepts and misconceptions in in vivo corneal assessment.
- To analyze the impact of corneal viscoelasticity on clinical data interpretation.
- To compare air-puff deformation devices with different profiles.
Main Methods:
- Literature review of biomechanical concepts.
- Analysis of in vivo corneal deformation via air-puff.
- Comparison of clinical devices (temporal and magnitude profiles).
Main Results:
- Identified common misconceptions in corneal biomechanical assessment.
- Highlighted the significant role of corneal viscoelasticity in data interpretation.
- Detailed differences between two air-puff devices.
Conclusions:
- Accurate understanding of biomechanics is crucial for in vivo corneal assessment.
- Corneal viscoelasticity significantly influences clinical outcomes.
- Device-specific profiles impact air-puff deformation measurements.
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