Related Experiment Video
Updated: Apr 29, 2026

Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Investigating the interaction of sunset yellow aggregates and 6-fluoro-2-naphthoic acid: increasing probe molecule
1School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, UK.
Abstract:
The interaction of small molecules with non-covalent assemblies is of wide interest. The use of a magnetically active reporter nucleus allows information to be obtained in the presence of spectral overlap or in cases of high dynamic range. In this paper, we explore the interaction of a larger probe molecule, 6-fluoro-2-naphthoic acid with assemblies of sunset yellow using (19)F chemical shifts and diffusion NMR methods. Comparing the observations with previous studies using fluorophenols, 6-fluoro-2-naphthoic acid prefers to associate as clusters at the ends of the sunset yellow stacks.
Related Concept Videos
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Nucleophilic Aromatic Substitution: Elimination–Addition
2° Amines to N-Nitrosamines: Reaction with NaNO2

