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Updated: Apr 28, 2026
05:56
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016
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[The cornea in high axial myopia].
O Touzeau1, T Gaujoux2, O Sandali3
1Service d'ophtalmologie, hôpital Saint-Antoine, AP-HP, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France; Institut de la vision, Inserm, U968, CNRS, UMR_7210, 17, rue Moreau, 75012 Paris, France.
Journal Francais D'Ophtalmologie
|June 1, 2014
Summary
High myopia shares similar corneal characteristics with emmetropic eyes, except for increased corneal toricity. This suggests corneal toricity may influence the development of high myopia.
Area of Science:
- Ophthalmology
- Corneal topography
- Refractive error
Context:
- High myopia is characterized by excessive axial elongation of the eye.
- Understanding corneal biomechanics is crucial for managing refractive errors.
- Previous studies have not fully elucidated corneal characteristic differences between high myopia and emmetropia.
Purpose:
- To compare corneal characteristics between eyes with high myopia and those with no spherical ametropia.
- To investigate the role of corneal toricity in the development of high myopia.
Summary:
- A study involving 105 high myopia patients and 105 emmetropic controls used Orbscan and ultrasonic pachymetry.
- Results showed similar corneal thickness, diameter, and irregularity between groups.
- Eyes with high myopia exhibited significantly higher corneal cylinder (toricity) and steeper maximal keratometry compared to controls.
Impact:
- High myopia development appears independent of most corneal characteristics, except for toricity.
- Corneal toricity may play a role in perturbing emmetropization mechanisms, potentially leading to high myopia.
- Findings contribute to understanding the multifactorial etiology of high myopia.
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