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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...

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Updated: Apr 28, 2026

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

Published on: June 9, 2018

Methods and considerations for longitudinal structural brain imaging analysis across development.

Kathryn L Mills¹, Christian K Tamnes²

¹Institute of Cognitive Neuroscience, University College London, London, UK; Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA.

Developmental Cognitive Neuroscience

|June 1, 2014

Summary

This summary is machine-generated.

Magnetic resonance imaging (MRI) reveals extensive human brain development across the lifespan. This review details MRI methods for tracking structural brain changes and discusses best practices for future research.

Keywords:

Adolescence Childhood DTI MRI Maturation Morphometry

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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Last Updated: Apr 28, 2026

Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease

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Published on: June 9, 2018

3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse

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Published on: May 19, 2015

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Area of Science:

Neuroscience
Developmental Biology
Medical Imaging

Background:

Magnetic resonance imaging (MRI) provides in vivo measurement of the human brain.
Longitudinal studies using MRI track brain changes throughout the lifespan.
Structural and histological data reveal multifaceted brain development.

Purpose of the Study:

To review common MRI measurements of structural brain development in children and adolescents.
To update knowledge on structural brain development using longitudinal data.
To discuss current image processing, analysis, and modeling techniques.

Main Methods:

Focus on brain morphometry: volume, cortical thickness, surface area, and folding patterns.
Incorporate measurements from diffusion tensor imaging (DTI).
Integrate findings from multiple longitudinal investigations.

Main Results:

MRI reveals extended and multifaceted brain development.
Structural development relates to other biological development and physiological mechanisms.
Current techniques offer new avenues for exploration.

Conclusions:

MRI is crucial for understanding in vivo brain development.
Standardized methods and cautious interpretation are vital for longitudinal studies.
This review aims to guide future research and promote discussion on best practices.