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Optimizing Minimally Invasive Spine Surgery: A Fully 3D CT O-Arm Navigated Workflow in MIS TLIF
Published on: October 17, 2025
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Cost-effectiveness analysis in minimally invasive spine surgery
Lutfi T Al-Khouja1, Eli M Baron, J Patrick Johnson
1Departments of Neurosurgery and.
Neurosurgical Focus
|June 3, 2014
Summary
Minimally invasive spine surgery (MISS) appears to be more cost-effective than open surgery, showing cost savings and better patient outcomes. However, standardized reporting is needed for definitive conclusions on cost-effectiveness.
Area of Science:
- Health Economics
- Neurosurgery
- Surgical Innovation
Background:
- The healthcare system is increasingly focused on value-based care, emphasizing cost-effectiveness and utility.
- This shift necessitates evaluating the economic impact of various medical interventions, including surgical procedures.
Purpose of the Study:
- To analyze the available literature on the costs associated with minimally invasive spine surgery (MISS).
- To compare the cost-effectiveness of MISS with traditional open spine surgery.
Main Methods:
- A comprehensive literature review was conducted using PubMed, the Cost-Effectiveness Analysis (CEA) Registry, and the National Health Service Economic Evaluation Database (NHS EED).
- Studies reporting costs for MISS were included; articles lacking cost, CEA, CUA, QALY, quality, or outcomes data were excluded.
Main Results:
- Fourteen studies involving 12,425 patients were analyzed, comparing MISS to open procedures.
- MISS demonstrated cost savings ranging from 2.54% to 33.68% compared to open surgery.
- MISS was associated with shorter hospital stays (0.93–5.1 days vs. 1.53–12 days) and lower estimated blood loss (EBL) (10–392.5 ml vs. 55–535.5 ml).
Conclusions:
- Current literature on MISS costs lacks standardized reporting methods.
- Preliminary findings suggest MISS offers both cost savings and improved outcomes compared to open surgery.
- Further Level I CEA/CUA studies with standardized cost/QALY evaluations are required for definitive conclusions on MISS cost-effectiveness.
Keywords:
CEA = cost-effectiveness analysisCUA = cost-utility analysisEBL = estimated blood lossICER = incremental cost-effectiveness ratioLOS = length of stayMISS = minimally invasive spine surgeryNHS EED = National Health Service Economic Evaluation DatabasePLIF = posterior lumbar interbody fusionQALY = quality-adjusted life yearRCT = randomized controlled trialSSI = surgical site infectionTLIF = transforaminal lumbar interbody fusioncost analysiscost-effectiveness analysiscost-utility analysisminimally invasive surgeryspine
