Related Experiment Video
Updated: Apr 28, 2026

Mouse Round Spermatid Injection
Published on: January 26, 2024
Spermbots: potential impact for drug delivery and assisted reproductive technologies
Veronika Magdanz1, Oliver G Schmidt
1Institute for Integrative Nanosciences, IFW Dresden , Helmholtzstraße 20, 01069 Dresden , Germany.
Abstract:
Micromotors and nanomotors are an emerging research field that aims at achieving locomotion on the microscale for a variety of applications such as drug delivery, single cell manipulation, microsensors and lab-on-a-chip devices, just to point out a few. The enthusiastic development of hybrid micromotors harnessing biological power sources for physiologically compatible nano/microdevices has recently brought a lot of attention to the international research community that is looking for a solution for the actuation and locomotion on the microscale. This article describes the potential of sperm-driven micro-bio-robots in the biomedical field such as drug delivery or single cell manipulation. Herein, a specific potential of the sperm-driven micro-bio-robot is described that might have impact on the development of assisted reproductive technologies.
Related Concept Videos
Spermatogenesis
Factors Affecting Drug Distribution: Physiological Barriers
The capillary endothelial barrier allows only smaller molecules below 600 Da (Daltons) to pass through. It also restricts drugs like heparin that are bound to blood components, limiting their movement within the bloodstream.
The...
Sperm Transport
The maturation phase occurs in the epididymis, where sperm...
Infertility in Males
CRISPR
Fertilization

