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Esophageal Varices-II: Clinical Features and Management

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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
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Inflammatory bowel disease (IBD) encompasses two major chronic disorders—ulcerative colitis and Crohn’s disease—each characterized by relapsing episodes of gastrointestinal inflammation. Although they share certain clinical features, their patterns of involvement and manifestations differ in ways that aid diagnosis and guide management.Ulcerative ColitisUlcerative colitis is limited to the colon and rectum and involves continuous inflammation of the mucosal layer. The...
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Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
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The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
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Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
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Gastrointestinal bleeding.

Gary A Neidich1, Sarah R Cole1

  • 1Department of Pediatrics, Sanford School of Medicine of the University of South Dakota, and Sanford Children's Specialty Clinic, Sioux Falls, SD.

Pediatrics in Review
|June 4, 2014
PubMed
Summary
This summary is machine-generated.

For severe upper gastrointestinal bleeding in children, intravenous proton pump inhibitors are recommended. Endoscopy is advised for severe bleeding, with capsule endoscopy considered if endoscopy is inconclusive.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Hemorrhage Management
  • Endoscopic Diagnostics

Background:

  • Severe upper gastrointestinal tract bleeding in children presents significant clinical challenges.

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  • Current management strategies require evidence-based guidelines for optimal patient outcomes.