Related Experiment Video
Updated: Apr 28, 2026

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
Published on: August 1, 2025
Gastrointestinal bleeding
Gary A Neidich1, Sarah R Cole1
1Department of Pediatrics, Sanford School of Medicine of the University of South Dakota, and Sanford Children's Specialty Clinic, Sioux Falls, SD.
Insights
For severe upper gastrointestinal bleeding in children, intravenous proton pump inhibitors are recommended. Endoscopy is advised for severe bleeding, with capsule endoscopy considered if endoscopy is inconclusive.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Hemorrhage Management
- Endoscopic Diagnostics
Background:
- Severe upper gastrointestinal tract bleeding in children presents significant clinical challenges.
- Current management strategies require evidence-based guidelines for optimal patient outcomes.
Abstract:
• On the basis of strong research evidence, children with severe upper gastrointestinal tract bleeding should be treated with intravenous proton pump inhibitors. • On the basis of some research evidence and consensus, children with severe gastrointestinal bleeding should be evaluated by endoscopy. • On the basis of some research evidence and consensus, children in whom endoscopy has not been able to confirm a bleeding source should be considered for capsule endoscopy.
Related Concept Videos
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Inflammatory Bowel Disease IV: Clinical Manifestations
Esophageal Varices-I: Introduction
Other Disorders of Digestive System
