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Updated: Apr 28, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
[Effect of exercise on high density lipoprotein subpopulations and blood pressure]
Olga A Nieto1, Diana M García1, Jorge A Jiménez1
1Facultad de Ciencias de la Salud, Universidad del Quindío, Armenia, Colombia, dmgarcia@uniquindio.edu.co.
Objective:
Determine the relationship of exercise with serum levels of apoA-I and HDL2 and HDL3, subpopulations in hypertensive individuals from the city of Armenia - Quindío.
Methods:
The interventions were two months of exercise. Blood pressure was taken with the recommendations of the Ministry of Health of Colombia. HDL subpopulations were measured with the method of precipitate ionic and the apoA-I was measured using nephelometry of Bindig site.
Results:
Descriptive and inferential statistics were used for data analysis. A total of 160 patients of whom 125 remained until the end of the project were gathered, that is, there was a 78.12 % retention, 28 % did the exercise. The analysis showed a highly significant reduction of systolic and diastolic blood pressure, higher in people who did exercise. The HDL were below normal before exercise, significantly increased with exercise but still remained below the reference values, the HDL2 increased significantly, while HDL3 decreased with normal levels of apoA-I.
Conclusion:
This study shows that exercise increases the total HDL, but the most important is that exercise modified the HDL subpopulations in a relationship that favors those which seem to have ateroprotective properties. The evidence of the interrelationship between protective factors provides new arguments for public health actions against the cardiovascular risk and hypertension.
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