Related Experiment Video
Updated: Apr 28, 2026
11:02
Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
20.8K
[Small cell carcinoma of the bladder]
Toru Sakatani1, Yosuke Shimizu1, Yoshio Sugino1
1The Department of Urology, Kyoto University Graduate School of Medicine.
Hinyokika Kiyo. Acta Urologica Japonica
|June 5, 2014
Summary
Neoadjuvant chemotherapy followed by cystectomy may cure small cell carcinoma of the bladder without metastatic disease. This bladder cancer treatment offers long-term survival for eligible patients.
Area of Science:
- Urology
- Oncology
- Medical Research
Context:
- Small cell carcinoma of the bladder is a rare and aggressive cancer.
- Treatment outcomes for this condition are often poor, especially in advanced stages.
Purpose:
- To evaluate the effectiveness of neoadjuvant chemotherapy followed by cystectomy in treating small cell carcinoma of the bladder.
- To compare survival rates between patients treated with this combined approach versus other methods.
Summary:
- A retrospective review of 11 patients with small cell carcinoma of the bladder was conducted.
- Patients without metastatic disease who received neoadjuvant chemotherapy followed by cystectomy demonstrated significantly longer survival compared to those receiving other treatments.
- Three patients treated with this approach are alive and cancer-free with long-term survival.
Impact:
- Neoadjuvant chemotherapy followed by cystectomy shows promise as a curative treatment for non-metastatic small cell carcinoma of the bladder.
- This finding could influence treatment strategies for this rare bladder cancer.
- Further research is warranted to validate these results in larger cohorts.
Related Concept Videos
01:23Urinary Bladder
4.7K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
4.7K
01:30Skin Cancer
5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K