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Updated: Apr 28, 2026

A Fluorescence-based Assay for Characterization and Quantification of Lipid Droplet Formation in Human Intestinal Organoids
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Intestinally Targeted Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitors Robustly Suppress Postprandial

Michael H Serrano-Wu1, Gary M Coppola1, Yongjin Gong1

  • 1Departments of Global Discovery Chemistry, Cardiovascular and Metabolism, Metabolism and Pharmacokinetics, and Translational Sciences, Novartis Institutes for Biomedical Research , 100 Technology Square, Cambridge Massachusetts 02139, United States.

ACS Medicinal Chemistry Letters
|June 6, 2014
PubMed

Keywords:
DGAT1effluxtriglyceride synthesis

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