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The relation between serum vitamin D levels and blood pressure: a population-based study
Fatemeh Ardeshir Larijani1, Seyed Mohammad Kalantar Motamedi1, Abbas Ali Keshtkar1
1Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran emrc@tums.ac.ir.
Acta Medica Iranica
|June 6, 2014
Summary
This study found a weak positive association between vitamin D levels and systolic blood pressure in the Iranian population. However, this link diminished after adjusting for age and Body Mass Index (BMI).
Area of Science:
- Endocrinology
- Cardiovascular Health
- Nutritional Science
Background:
- Vitamin D deficiency is a potential factor linked to elevated blood pressure.
- Understanding this relationship is crucial for public health initiatives.
Purpose of the Study:
- To investigate the association between serum vitamin D levels and blood pressure in a large Iranian adult population.
- To determine if vitamin D influences hypertension risk.
Main Methods:
- Cross-sectional study utilizing data from 2508 adults (20-70 years) from the Iran Multicenter Osteoporosis Study (IMOS).
- Serum vitamin D levels and blood pressure were measured.
- Multivariate regression models were employed to analyze the association, adjusting for covariates.
Main Results:
- A statistically significant difference in mean vitamin D levels was observed between individuals with Stage I hypertension and other blood pressure groups.
- A weak positive association was found between serum vitamin D concentration and systolic blood pressure.
- This association lost statistical significance after adjusting for age and Body Mass Index (BMI).
Conclusions:
- The study identified a weak, positive association between vitamin D and systolic blood pressure in the Iranian population.
- Further research is recommended to explore the influence of ethnicity and genetic factors on this relationship, given discrepancies with prior studies.
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