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Updated: Apr 28, 2026

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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
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Serious rectal bleeding complicating suction rectal biopsy in a child
The West Virginia Medical Journal
|June 7, 2014
Summary
Rectal suction biopsy is generally safe for Hirschsprung
Area of Science:
- Pediatric Surgery
- Gastroenterology
Background:
- Rectal suction biopsy is a primary diagnostic tool for suspected Hirschsprung's disease.
- The procedure typically has a good safety profile, especially in neonates.
Observation:
- A 2-year-old child with suspected Hirschsprung's disease underwent rectal suction biopsy.
- This patient experienced delayed bleeding post-procedure, necessitating a blood transfusion.
Findings:
- This case represents the first reported instance of significant delayed bleeding in an older child (over one year) following rectal suction biopsy.
- While rare, serious complications can occur, even in older pediatric patients.
Implications:
- Pediatric gastroenterologists and surgeons should be aware of the potential for delayed bleeding complications in older children undergoing rectal suction biopsy.
- Enhanced vigilance and potentially modified post-procedure monitoring may be warranted for this patient group.
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