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Published on: October 11, 2024
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Diverticulitis occurs early after lung transplantation
Eric S Larson1, Hassan A Khalil1, Anne Y Lin1
1Department of Surgery, UCLA, Los Angeles, CA.
The Journal of Surgical Research
|June 11, 2014
Summary
Diverticulitis is common in lung transplant recipients, occurring within two years post-transplant. Most patients require surgery, highlighting the need for early diagnosis and treatment in this high-risk group.
Area of Science:
- Gastroenterology
- Transplant Surgery
- Immunology
Background:
- Lung transplantation recipients face an elevated risk of diverticulitis.
- The incidence and natural history of diverticulitis in this population are not well-defined.
- Identifying risk factors is crucial for managing diverticulitis post-lung transplant.
Purpose of the Study:
- To determine the incidence of diverticulitis in lung transplant recipients.
- To identify patient and transplant-related factors associated with diverticulitis risk.
- To characterize the natural history and management outcomes of diverticulitis in this cohort.
Main Methods:
- Retrospective single-institution study.
- Evaluation of lung transplant recipients from May 2008 to July 2013.
- Analysis of patient factors, diverticulitis incidence, timing, and management outcomes.
Main Results:
- 14 out of 314 (4.5%) lung transplant recipients developed diverticulitis.
- All diverticulitis cases (100%) occurred within two years post-transplantation.
- 57% required surgery with a 12.5% mortality rate; 43% were managed medically.
Conclusions:
- Diverticulitis is a frequent complication after lung transplantation, with higher incidence than in the general population.
- Diverticulitis typically manifests early post-transplant, often necessitating surgical intervention.
- Prompt medical management may prevent surgery; increased awareness can lead to earlier diagnosis and treatment.
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