Related Experiment Video
Updated: Apr 28, 2026

03:47
A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
Published on: October 25, 2024
819
Metastatic spinal abscesses from diabetic foot osteomyelitis
Shang Shaho1, Shaila Khan1, M S Bobby Huda1
1Department of Diabetes and Metabolism, Barts and the London NHS Trust, London, UK.
BMJ Case Reports
|June 13, 2014
Summary
A patient with diabetes experienced sepsis from a foot ulcer, leading to spinal cord abscesses and severe paralysis. Despite treatment, the neurological damage required extensive rehabilitation.
Area of Science:
- Neurology
- Infectious Diseases
- Diabetology
Background:
- A 66-year-old male with type 2 diabetes, nephropathy, and neuropathy presented with a severe infected neuropathic ulcer.
- Comorbidities included long-standing diabetes with complications.
Observation:
- The patient rapidly deteriorated with sepsis and right lobar pneumonia.
- Methicillin-sensitive Staphylococcus aureus was identified.
- Flaccid paraparesis developed, with MRI revealing multiple epidural abscesses and likely spinal cord infarction.
Findings:
- The spinal epidural abscesses were not amenable to surgical intervention.
- Sepsis resolved, but severe paraparesis persisted.
- The patient required specialized spinal rehabilitation.
Implications:
- This case highlights the severe neurological complications that can arise from diabetic foot infections.
- Early recognition and management of sepsis and spinal complications are crucial.
- Neuropathic ulcers in diabetic patients pose a significant risk for invasive infections and neurological sequelae.
Related Concept Videos
Diabetic Foot Ulcer
29
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
29
Brain Abscess l: Introduction
16
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
16
Diabetic Neuropathy
49
DefinitionDiabetic neuropathy is nerve damage caused by long-standing diabetes mellitus. It results directly from prolonged high blood sugar levels.PathophysiologyThe pathophysiology of diabetic neuropathy involves both metabolic and vascular disturbances triggered by chronic hyperglycemia.Metabolic injury: Elevated glucose levels activate the polyol pathway within nerve cells, leading to the accumulation of sorbitol and fructose. This increases oxidative stress, disrupts normal nerve...
49