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Updated: Apr 28, 2026

Minimally Invasive Cisterna Magna Injection Model for Leptomeningeal Metastasis Studies in Mice
Published on: May 23, 2025
[A case of lateral ventricle metastasis from gastric carcinoma]
Jumpei Oshita1, Shinji Ohba, Yoko Itou
1Department of Neurosurgery, National Hospital Organization Kure Medical Center and Chugoku Cancer Center.
Abstract:
Metastatic brain tumors of the lateral ventricles are rare. Approximately half of the reported cases have originated from renal carcinoma;to the best of our knowledge, only 1 case originating from gastric carcinoma has been reported. A 57-year-old man presented with dull headache, left hemiparesis, and constructional apraxia of the right upper extremity. He had undergone gastrectomy for gastric carcinoma 8 years previously. Magnetic resonance imaging revealed an enhanced tumor extending from the right caudate nucleus to the right lateral ventricle with peritumoral edema. Complete resection of the tumor was achieved via the right transcallosal approach. The histopathological diagnosis was metastasis from the gastric carcinoma. After the resection, the patient temporarily showed a lack of spontaneity and extrapyramidal signs of the right upper and lower limbs;his condition improved after 3 weeks. He was discharged 2 months after the surgery, without any neurological deficits. Patients with tumors of the lateral ventricles may present with various characteristic neurological symptoms in the perioperative period;therefore, a thorough neurological examination is necessary.

