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Warts (non-genital).

Steven King-Fan Loo¹, William Yuk-Ming Tang

¹Hong Kong Adventist Hospital, Hong Kong SAR.

BMJ Clinical Evidence

|June 13, 2014

Summary

This summary is machine-generated.

This systematic review examines various treatments for non-genital warts caused by human papillomavirus (HPV). It evaluates the effectiveness and safety of interventions like cryotherapy and topical salicylic acid.

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Area of Science:

Dermatology
Infectious Diseases
Evidence-Based Medicine

Background:

Warts are benign skin growths caused by over 100 types of human papillomavirus (HPV).
Transmission occurs through skin contact, with risk factors including immunosuppression and use of communal facilities.
In healthy individuals, warts typically resolve spontaneously due to natural immunity.

Purpose of the Study:

To systematically review the effects of various treatments for non-genital warts.
To assess the effectiveness and safety of different therapeutic interventions for common warts.

Main Methods:

Systematic review of 17 studies identified through comprehensive database searches (Medline, Embase, Cochrane Library) up to October 2013.
Inclusion of harms alerts from regulatory agencies like the FDA and MHRA.
GRADE evaluation of the quality of evidence for reviewed interventions.

Main Results:

Seventeen studies met the inclusion criteria for the review.
Evidence quality for various interventions was assessed using the GRADE system.
The review synthesizes data on multiple wart treatment modalities.

Conclusions:

The review presents findings on the effectiveness and safety of diverse wart treatments.
Interventions evaluated include intralesional bleomycin, cryotherapy, contact immunotherapy, and topical salicylic acid.
Other treatments assessed are intralesional candida antigen, duct tape occlusion, photodynamic therapy, pulsed dye laser, and surgical procedures.