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Exercise intervention studies in patients with peripheral neuropathy: a systematic review
Fiona Streckmann1, Eva M Zopf, Helmar C Lehmann
1Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933, Cologne, Germany, f.streckmann@dshs-koeln.de.
Sports Medicine (Auckland, N.Z.)
|June 15, 2014
Summary
Balance exercises are most effective for managing peripheral neuropathy (PNP) symptoms. Endurance training is also beneficial, particularly for diabetic peripheral neuropathy (DPN).
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Science
Background:
- Peripheral neuropathies (PNPs) are common, heterogeneous disorders causing sensory and/or motor deficits.
- PNPs can lead to significant disability and poor recovery.
- Exercise interventions show promise in mitigating PNP side effects.
Purpose of the Study:
- To systematically review exercise interventions for neuropathic patients.
- To evaluate the potential benefits of exercise in managing PNPs.
Main Methods:
- Systematic review of studies from PubMed, MEDPILOT, and Cochrane.
- Inclusion of randomized controlled trials and controlled clinical trials.
- Grading of study quality using the Oxford Levels of Evidence.
Main Results:
- Eighteen studies met inclusion criteria; quality varied from low to very high.
- Balance exercises demonstrated the most significant improvements in motor and sensory symptoms across all PNP types.
- Endurance training showed potential in preventing and reducing progression of diabetic peripheral neuropathy (DPN).
Conclusions:
- Balance training is the most effective exercise intervention for PNPs.
- Endurance training is important for metabolically-induced neuropathies.
- Further high-quality research is needed to establish evidence-based clinical recommendations.
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