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Is malnutrition a problem for multiple sclerosis patients?

Mine Hayriye Sorgun1, Canan Yucesan1, Cuneyt Tegin2

  • 1Department of Neurology, Ankara University School of Medicine, İbni Sina Hospital, Samanpazarı, Ankara, Turkey.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|June 17, 2014
PubMed
Summary

Malnutrition is more common in multiple sclerosis (MS) patients than in those with other chronic neurological diseases. However, malnutrition in MS is not linked to disease type, duration, or disability level, suggesting further research is needed.

Keywords:
AlbuminMalnutritionMultiple sclerosis

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Area of Science:

  • Neurology
  • Clinical Nutrition
  • Epidemiology

Background:

  • Nutritional issues are frequently reported in multiple sclerosis (MS) cases.
  • The prevalence of malnutrition among MS patients remains undetermined.
  • Understanding malnutrition's frequency in MS is crucial for patient care.

Purpose of the Study:

  • To determine the prevalence of malnutrition in multiple sclerosis (MS) patients.
  • To compare malnutrition rates in MS versus other chronic neurological diseases.
  • To investigate the association between malnutrition and MS characteristics (type, duration, disability).

Main Methods:

  • A study involving 102 MS patients and 50 controls with other chronic neurological diseases.
  • Assessment included neurological and functional disability scores (Kurtzke Functional System Scale).
  • Chronic malnutrition defined by low serum albumin (<3.5 g/dl) with normal inflammatory markers (ESR, CRP).

Main Results:

  • Chronic malnutrition was diagnosed in 12 MS patients and 1 control (p=0.062), indicating a trend towards higher prevalence in MS.
  • Malnutrition in MS patients was not significantly associated with MS type, disease duration, number of attacks, or disability status.
  • The study suggests malnutrition is more prevalent in MS patients compared to other chronic neurological conditions.

Conclusions:

  • Malnutrition appears more common in multiple sclerosis patients than in other chronic neurological diseases.
  • Malnutrition in MS is independent of disease course, duration, and disability.
  • Further prospective studies with larger MS cohorts are recommended to validate these findings.