Related Experiment Video
Updated: Apr 28, 2026
10:40
Uniportal Full Endoscopic Posterolateral Transforaminal Lumbar Interbody Fusion
Published on: June 6, 2025
1.2K
[Axial lumbar interbody fusion: prospective monocentric study]
Summary
The percutaneous AxiaLIF technique for L5-S1 fixation shows high fusion rates (95.6%) and significant improvements in pain (VAS) and function (ODI) for complex spinal cases. This minimally invasive approach offers a safe and effective alternative to traditional surgeries.
Area of Science:
- Spine Surgery
- Minimally Invasive Spine Procedures
- Spinal Fusion Techniques
Background:
- The L5-S1 segment is frequently affected by degenerative conditions, spondylolisthesis, and stenosis.
- Conventional surgical approaches for L5-S1 fusion can be challenging in specific patient populations, including those who are overweight or have undergone prior abdominal surgeries.
- Percutaneous techniques offer potential advantages in minimizing surgical invasiveness and patient recovery time.
Purpose of the Study:
- To evaluate the clinical and radiographic outcomes of L5-S1 fixation using the percutaneous axial lumbar interbody fusion (AxiaLIF) technique.
- To assess the efficacy and safety of AxiaLIF in patients with specific indications, including prior surgeries and anatomical challenges.
Main Methods:
- A prospective study of 23 patients (average age 48.2 years) undergoing AxiaLIF for L5-S1 fixation.
- Patients had pre-existing posterior stabilization or specific indications like spondylolisthesis, spondylosis, stenosis, obesity, or prior abdominal/retroperitoneal surgery.
- Clinical outcomes were assessed using the Oswestry Disability Index (ODI) and Visual Analog Scale (VAS), with radiographic evaluation for bone union and stability over an average of 40.4 months.
Main Results:
- Significant improvements were observed in VAS scores (56.1% at 2 years) and ODI scores (57.8% at 2 years).
- A high fusion rate of 95.6% was achieved, with a stable L5-S1 segment in all patients.
- 91.3% of patients expressed willingness to undergo the procedure again, and no major complications like screw breakage or neurovascular damage were reported.
Conclusions:
- The AxiaLIF technique is a viable and effective option for L5-S1 interbody fusion, particularly in patients with contraindications to conventional surgery.
- This percutaneous approach demonstrates comparable clinical outcomes and fusion success rates to traditional fusion methods.
- AxiaLIF offers a safe alternative with rare complications, suitable for complex L5-S1 stabilization needs.
