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Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Current and future trends in the diagnosis of periprosthetic hip infection
Beau S Konigsberg1, Curtis W Hartman1, Angela L Hewlett2
1Department of Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, 981080 Nebraska Medical Center, Omaha, NE 68198-1080, USA.
Abstract:
The challenge of confirming the diagnosis of prosthetic hip infection is two-fold. First, the presentation of the patient with a prosthetic hip infection often has limited or few subjective complaints and physical findings, nonconfirmatory inflammatory laboratory markers, and negative culture results. Second, there has not been consistent agreement of the definition of prosthetic join infection. Recent work by the Musculoskeletal Infection Society has created a new uniform definition for research and clinical use that may improve the ability to accurately diagnose prosthetic hip infections individually and share data among different sites for research collaboration.
Insights
Diagnosing prosthetic hip infections is difficult due to vague symptoms and inconsistent definitions. A new uniform definition may improve diagnosis and research collaboration for prosthetic joint infections.
Area of Science:
- Orthopedics
- Infectious Diseases
- Medical Diagnostics
Background:
- Prosthetic hip infections present diagnostic challenges with subtle clinical signs.
- Inflammatory markers and cultures are often non-confirmatory.
- Lack of a standardized definition complicates diagnosis and research.
Purpose of the Study:
- To address the diagnostic challenges in prosthetic hip infections.
- To highlight the need for a uniform definition.
- To introduce a new definition for improved accuracy and collaboration.
Main Methods:
- Review of current diagnostic criteria for prosthetic hip infections.
- Analysis of the limitations of existing diagnostic methods.
- Introduction of the Musculoskeletal Infection Society's uniform definition.
Main Results:
- The new uniform definition offers a standardized approach.
- Improved diagnostic accuracy for individual cases is anticipated.
- Facilitation of multi-site research collaboration is expected.
Conclusions:
- A uniform definition is crucial for accurate prosthetic hip infection diagnosis.
- The new definition enhances diagnostic consistency and research capabilities.
- This advancement aids in managing prosthetic joint infections effectively.
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