Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

11.0K
Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
11.0K
Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

9.1K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
9.1K
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

16.0K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
16.0K
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.0K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.0K
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

9.4K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
9.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Potential evaluation of SULT1A3 as an early diagnostic marker for nasopharyngeal carcinoma: a study based on serum proteomics screening and ELISA validation.

BMC cancer·2026
Same author

Bimetallic Steels: A Structured Review of Fabrication Routes, Material Properties, and Component Performance.

Materials (Basel, Switzerland)·2026
Same author

The membrane receptor Basigin facilitates WSSV infection by binding envelope proteins and suppressing antiviral gene expression in shrimp.

Fish & shellfish immunology·2026
Same author

Qishen paste improves cardiac conduction in heart failure by regulating cardiac resident macrophage Connexin43.

Journal of ethnopharmacology·2026
Same author

Systemic inflammation response index as an independent predictor of unfavorable prognosis and its application in risk stratification in patients with aneurysmal subarachnoid hemorrhage.

Frontiers in neuroscience·2026
Same author

Mendelian Randomization Analysis of the Relationship between Neurotransmitter-related Genes and Cancer: Insights from Multi-omics Data.

Current topics in medicinal chemistry·2026
Same journal

Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

Optics letters·2026
Same journal

E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

Optics letters·2026
Same journal

Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

Optics letters·2026
Same journal

Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

Optics letters·2026
Same journal

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026
Same journal

Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

Optics letters·2026
See all related articles

Related Experiment Video

Updated: Apr 27, 2026

Fabrication and Operation of a Nano-Optical Conveyor Belt
11:10

Fabrication and Operation of a Nano-Optical Conveyor Belt

Published on: August 26, 2015

11.2K

Optimized optical "tractor beam" for core-shell nanoparticles.

Neng Wang, Wanli Lu, Jack Ng

    Optics Letters
    |July 1, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Core-shell nanoparticles can create optical tractor beams by enhancing forward scattering. Researchers used Bessel beams and Maxwell stress tensor theory to optimize pulling forces and confirm nanoparticle stability.

    More Related Videos

    Optical Trapping of Nanoparticles
    13:39

    Optical Trapping of Nanoparticles

    Published on: January 15, 2013

    27.3K
    Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System
    09:48

    Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

    Published on: June 30, 2018

    9.9K

    Related Experiment Videos

    Last Updated: Apr 27, 2026

    Fabrication and Operation of a Nano-Optical Conveyor Belt
    11:10

    Fabrication and Operation of a Nano-Optical Conveyor Belt

    Published on: August 26, 2015

    11.2K
    Optical Trapping of Nanoparticles
    13:39

    Optical Trapping of Nanoparticles

    Published on: January 15, 2013

    27.3K
    Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System
    09:48

    Construction and Operation of a Light-driven Gold Nanorod Rotary Motor System

    Published on: June 30, 2018

    9.9K

    Area of Science:

    • Nanophotonics and Plasmonics
    • Optical forces and manipulation

    Background:

    • Core-shell nanoparticles with metallic cores and dielectric shells exhibit dual electric and magnetic dipolar resonances.
    • These resonances enable enhanced forward scattering and suppressed backward scattering, crucial for optical tractor beam applications.

    Purpose of the Study:

    • To demonstrate and optimize optical pulling forces using core-shell nanoparticles.
    • To investigate the role of first-order Bessel beams and polarization in inducing these forces.
    • To verify the transverse stability of the nanoparticles under damping conditions.

    Main Methods:

    • Generalized Lorenz-Mie theory for scattering analysis.
    • Maxwell stress tensor formulation for calculating optical forces.
    • Linear stability analysis and dynamical simulations for assessing nanoparticle stability.

    Main Results:

    • Optical pulling forces were successfully induced and optimized in core-shell nanoparticles.
    • First-order Bessel beams with specific polarizations were identified as effective for generating these forces.
    • The transverse stability of the nanoparticles was confirmed, even in the presence of ambient damping.

    Conclusions:

    • Core-shell nanoparticles are promising for optical tractor beam applications.
    • Bessel beams offer a viable method for controlling optical pulling forces.
    • The demonstrated stability ensures the practical feasibility of these nanoparticle-based optical manipulation systems.