Related Experiment Video
Updated: Apr 27, 2026

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
The potential of metabonomics in drug safety and toxicology
1Department of Biochemistry, Tennis Court Road, University of Cambridge, Cambridge, UK CB2 1GA.
Abstract:
Metabonomics (or metabolomics) defines a global profile of the metabolites in a cell, tissue or organism using either (1)H NMR spectroscopy or mass spectrometry in conjunction with statistical pattern recognition. Unlike other functional genomic tools, it is high-throughput and cheap on a per sample basis, providing a rapid screen for large scale drug toxicity testing and screening of large populations. However, for its widespread use in toxicology there is an urgent need for biomarker databases.:
Related Concept Videos
Toxicokinetics: Overview
Drug Toxicity: Dose-Dependent Reactions
Pharmacogenetics of Drug Metabolism: Overview
Measurement of Bioavailability: Pharmacodynamic Methods
Toxicity Testing in Animals
Drug toxicity: Drug–Drug Interaction

