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Advances in virtual screening

Ingo Muegge¹, Scott Oloff¹

¹Boehringer Ingelheim Pharmaceuticals Inc., 900 Ridgebury Road, Ridgefield, P.O. Box 368, CT 06877-368, USA.

Drug Discovery Today. Technologies

|April 15, 2024

Abstract:

Although the term virtual screening as the in silico analog of high throughput screening has been coined only a decade ago, virtual screening is now a widespread lead identification method in the pharmaceutical industry. A myriad of different methods have been developed exploiting the growing library of target structures and assay data as a basis for finding new lead structures. Exploiting synergies between different methods best utilizes the information available and is at the center of recent developments.

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