Related Experiment Video
Updated: Apr 27, 2026

Intra-lymph Node Injection of Biodegradable Polymer Particles
Published on: January 2, 2014
Subcutaneous drug delivery and the role of the lymphatics
Danielle N McLennan1, Christopher J H Porter2, Susan A Charman1
1Centre for Drug Candidate Optimisation, Victorian College of Pharmacy, Monash University, 381 Royal Parade, Parkville, Vic. 3052, Australia.
Abstract:
Subcutaneous injections are widely utilised as a delivery route for compounds with limited oral bioavailability or as a means to modify or extend the release profile. In this review, factors affecting absorption from the subcutaneous space are discussed with particular emphasis on differential drug absorption into either the underlying blood or lymphatic capillaries. Formulation and targeted delivery approaches, which utilise the subcutaneous administration route, are reviewed with reference to associated technologies and future challenges.:
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