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Updated: Apr 27, 2026
Author Spotlight: Point-of-Care Ultrasound for Gastric Content Assessment and Risk Stratification in Perioperative Care
Published on: September 22, 2023
Gastric residual volume by magnetic ressonance after intake of maltodextrin and glutamine: a randomized double-blind,
Luigi R Brianez1, Cervantes Caporossi1, Yure W de Moura2
1Departamento de Cirurgia, Faculdade de Medicina, Universidade Federal de Mato Grosso, Cuiabá, MT, Brasil.
Context:
The addition of glutamine in preoperative drinks may enhance the benefits of carbohydrate alone.
Objectives:
To evaluate the gastric residual volume after the intake of a beverage containing carbohydrate plus glutamine.
Methods:
Eleven healthy volunteers (24-30 years-old) were randomized in a crossover fashion to intake 400 mL (4h before) and 200 mL (2h before) of a beverage containing either 12.5% maltodextrin (carbohydrate group) or 12.5% maltodextrin plus 15 g of glutamine (glutamine group) in two different moments 7 days apart. Magnetic ressonance was performed to measure the gastric residual volume (mL) 120 and 180 minutes after the last ingestion.
Results:
Gastric residual volume similar to basal condition was found after 2h and 3h of the intake of beverages. There was no difference in the mean ±SD GRV (mL) found at 120 minutes (carbohydrate group: 22.9±16.6 and glutamine group: 19.7±10.7) and at 180 minutes (carbohydrate group: 21.5±24.1 and glutamine group: 15.1±10.1) between the two drinks.
Conclusions:
Gastric emptying is efficient, and occurs in up to two hours after the intake of a beverage containing either carbohydrate alone or carbohydrate associated with glutamine. The addition of glutamine to carbohydrate-enriched drink seems to be safe for the use up to 2h before an operation.
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