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Ionophore-based optical sensors.

Günter Mistlberger1, Gastón A Crespo, Eric Bakker

  • 1Department of Inorganic and Analytical Chemistry, University of Geneva, CH-1211 Geneva 4, Switzerland; email: g.mistlberger@gmail.com , gaston.crespo@unige.ch , eric.bakker@unige.ch.

Annual Review of Analytical Chemistry (Palo Alto, Calif.)
|July 12, 2014
PubMed
Summary
This summary is machine-generated.

This review explores designing ionophore-based optical sensors (IBOS). It covers response functions, optical readout strategies like absorbance and fluorescence, and novel dynamic systems for improved sensor applications.

Keywords:
chemical mappingion sensingpH cross sensitivityphotoresponsive ion sensorsreferenced signals

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Area of Science:

  • Analytical Chemistry
  • Chemical Sensors
  • Optical Sensing

Background:

  • Ionophore-based optical sensors (IBOS) are crucial for detecting various analytes.
  • Effective sensor design requires understanding response functions and readout strategies.
  • Existing IBOS often need robust referencing for practical applications.

Purpose of the Study:

  • To provide a comprehensive overview of designing ionophore-based optical sensors (IBOS).
  • To compare exact response functions with simplified models.
  • To introduce advanced principles like dynamic response and exhaustive exchange for IBOS.

Main Methods:

  • Development and comparison of exact and simplified sensor response functions.
  • Review of absorbance and fluorescence as primary optical readout strategies.
  • Discussion of established and novel referencing techniques for optical sensors.

Main Results:

  • Established response functions and optical readout methods (absorbance, fluorescence) are detailed.
  • Less common but promising principles, dynamic response and exhaustive exchange, are introduced.
  • The potential of photoresponsive systems for dynamically switchable or regenerative IBOS is highlighted.

Conclusions:

  • Designing effective IBOS involves careful consideration of response functions and readout methods.
  • Advanced principles like dynamic response and photoresponsive systems offer new avenues for IBOS development.
  • Robust referencing is essential for real-world IBOS applications, with new strategies emerging.