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Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy
Published on: October 24, 2025
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The nonrecurrent laryngeal nerve: anatomic and electrophysiologic algorithm for reliable identification
Dipti Kamani1, Andre S Potenza, Claudio R Cernea
1Massachusetts Eye and Ear Infirmary, Division of Thyroid and Parathyroid Surgery, Boston, Massachusetts, U.S.A.
The Laryngoscope
|July 22, 2014
Summary
Intraoperative monitoring helps identify the nonrecurrent laryngeal nerve (NRLN) during thyroid surgery, reducing injury risk. This study provides an algorithm for reliable NRLN identification using electrophysiologic and anatomic parameters.
Area of Science:
- Neurosurgery
- Otolaryngology
- Thyroid Surgery
Background:
- The recurrent laryngeal nerve (RLN) is crucial for vocal cord function during thyroid surgery.
- Intraoperative monitoring (IONM) aids in RLN identification and management.
- The nonrecurrent laryngeal nerve (NRLN) presents a unique challenge due to its aberrant anatomy and increased risk of injury.
Purpose of the Study:
- To apply IONM for identifying the nonrecurrent laryngeal nerve (NRLN).
- To establish electrophysiologic and anatomic parameters for reliable NRLN identification.
- To develop an algorithm to prevent NRLN injury during thyroid surgery.
Main Methods:
- Retrospective study of thyroid surgeries utilizing IONM.
- Analysis of cases involving the nonrecurrent laryngeal nerve (NRLN).
- Preoperative and postoperative laryngoscopy documented for all cases; electrophysiologic parameters compared to normal nerves.
Main Results:
- The nonrecurrent laryngeal nerve (NRLN) was identified in 0.6% of cases (10 right-sided nerves).
- All identified NRLNs maintained normal laryngeal function postoperatively.
- Electrophysiologic parameters for NRLN identification were established using distal and proximal vagal nerve stimulation.
Conclusions:
- The nonrecurrent laryngeal nerve (NRLN) occurs in 0.6% of thyroid surgery patients.
- IONM with vagal stimulation reliably verifies NRLN presence intraoperatively.
- Anatomic subtypes and an electrophysiologic algorithm aid in early NRLN identification and injury prevention.

