Related Experiment Video
Updated: Apr 26, 2026
Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Frozen elephant trunk with total arch replacement for type A aortic dissections: Does acuity affect operative
Wei-Guo Ma1, Jun Zheng2, Wei Zhang3
1Department of Cardiovascular Surgery, Beijing Aortic Disease Center, Beijing Anzhen Hospital of Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, and Beijing Engineering Research Center of Vascular Prostheses, Beijing, China; Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences and State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease, Beijing, China; Aortic Institute at Yale-New Haven, Yale University School of Medicine, New Haven, Conn.
The Sun procedure for type A aortic dissection (TAAD) showed comparable early outcomes. However, factors like prior cerebrovascular disease and organ malperfusion significantly increased operative mortality risk.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Aortic Surgery
Background:
- Type A aortic dissection (TAAD) presents complex surgical challenges.
- The Sun procedure, involving frozen elephant trunk and total aortic arch replacement with a 4-branched graft, is a key surgical option.
- Understanding early outcomes and risk factors is crucial for patient management.
Purpose of the Study:
- Compare early outcomes of the Sun procedure in acute vs. chronic TAAD.
- Identify risk factors for operative mortality in TAAD patients.
- Assess the impact of TAAD acuity on operative mortality.
Main Methods:
- Univariate and multivariate analyses were performed.
- Clinical data from 803 TAAD patients undergoing the Sun procedure were analyzed.
- Risk factors for operative mortality were identified.
Main Results:
- Overall operative mortality was 6.5%.
- Acute TAAD showed higher rates of operative death, stroke, and respiratory morbidities.
- Previous cerebrovascular disease, organ malperfusion, extra-anatomic bypass, and prolonged cardiopulmonary bypass time were significant risk factors for mortality.
Conclusions:
- TAAD acuity was not a significant risk factor for operative mortality with the Sun procedure.
- Pre-existing cerebrovascular disease, malperfusion syndromes, concomitant bypass, and extended cardiopulmonary bypass times are associated with increased operative mortality risk.
