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Updated: Apr 26, 2026

Author Spotlight: Neuromotor Control and Recovery of Diaphragm Function Following Cervical Spinal Hemisection in Rats
Published on: June 14, 2024
Diaphragmatic pacing in spinal cord injury
Kevin Dalal1, Anthony F DiMarco2
1Department of Physical Medicine and Rehabilitation, University of Miami-Miller School of Medicine, 1120 North West 14th Street, Suite 936, Miami, FL 33136, USA.
Abstract:
After cervical spinal cord injuries, many patients are unable to sustain independent ventilation because of a disruption of diaphragm innervation and respiratory functioning. If phrenic nerve function is preserved, the patient may be able to tolerate exogenous pacing of the diaphragm via electrical stimulation. Previously this was accomplished by stimulation directly to the phrenic nerves, but may be accomplished less invasively by percutaneously stimulating the diaphragm itself. The benefits, when compared with mechanical ventilation, include a lower rate of pulmonary complications, improved venous return, more normal breathing and speech, facilitation of eating, cost-effectiveness, and increased patient mobility.
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