Related Experiment Video
Updated: Apr 26, 2026

Measurement of Basal and Forskolin-stimulated Lipolysis in Inguinal Adipose Fat Pads
Published on: July 21, 2017
[Research advances in the effects of excise and diet on LPL and its mechanism]
Abstract:
Lipoprotein lipase (LPL) plays a major role in the metabolism and transport of lipids by hydrolyzing core triglycerides (TG) in chylomicrons and very low density lipoprotein. LPL is mainly synthesized and secreted by fat cells, myocardial cells and skeletal muscle cells. The expression and activity of LPL are regulated by multiple factors, such as hormones, nutrition, exercise, PPARgamma, apolipoproteins, glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPIHBP1) and angiopoietin-like proteins (ANGPTL). After introducing advance in LPL structure and regulation, we review the effects of exercise and diet intervention on the expression and activity of LPL and its possible mechanism.
Related Concept Videos
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Cholesterol: Significance and Regulation
Considering cholesterol and...
Atherosclerosis III: Management
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
cAMP-dependent Protein Kinase Pathways

