[The study of hemodynamic changes in resuscitation of burns with two types of fluid regimens]

In dogs inflicted third-degree burns of 25% TBSA the hemodynamic changes were observed with resuscitation with whole blood (group A) or balanced saline solution (group B). The results showed that there were significant differences in time and degree of recovery between two groups. In group A, the recovery of cardiac index (CI) began after 18 hr of resuscitation, and it was delayed to 22 hr; in group B, 24 hr after the injury. Two groups showed significant differences in CI. The recovery in CI related mainly to stroke index. Moreover, group B animals showed higher pulmonary arterial pressure after injury. There was significant difference between the level at 48 hr and the pre-injury level. It could be concluded that resuscitation with whole blood did give more satisfactory resuscitation than pure crystalloid.