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Related Concept Videos

Salivary Glands and Saliva01:23

Salivary Glands and Saliva

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The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
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Exocrine Glands: Types of Secretions01:13

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Exocrine glands produce and release a variety of glandular products. Exocrine glands can be classified into serous, mucous, or mixed types based on their secretory products.
Serous glands produce watery secretions rich in digestive enzymes and proteins. The constituent cells of the serous gland have centrally located nuclei and eosinophilic secretory granules in the cytoplasm. The parotid gland is an example of a serous gland. It secretes saliva, which contains enzymes, such as lipases and...
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Adrenal Gland Disorders01:27

Adrenal Gland Disorders

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Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
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Accessory Organs01:31

Accessory Organs

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Accessory organs are those that participate in the digestion of food but do not come into direct contact with it like the mouth, stomach, or intestine do. Accessory organs secrete enzymes into the digestive tract to facilitate the breakdown of food.
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Lipid Digestion01:06

Lipid Digestion

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Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
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Oral Cavity01:11

Oral Cavity

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The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
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Related Experiment Video

Updated: Apr 26, 2026

Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers
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Salivary gland disorders.

Kevin F Wilson1, Jeremy D Meier1, P Daniel Ward1

  • 1University of Utah School of Medicine, Salt Lake City, UT, USA.

American Family Physician
|August 1, 2014
PubMed
Summary

Salivary gland disorders encompass infections, inflammation, and tumors, presenting acutely or chronically. Treatment varies from antibiotics and massage for infections to surgery for tumors, focusing on underlying causes and obstruction relief.

Area of Science:

  • Otolaryngology
  • Oral and Maxillofacial Surgery
  • Pathology

Background:

  • Salivary gland disorders present with diverse etiologies including inflammatory, infectious (bacterial, viral), and neoplastic causes.
  • These conditions manifest acutely, recurrently, or chronically, impacting salivary gland function and patient well-being.

Purpose of the Study:

  • To provide a comprehensive overview of salivary gland disorders, covering their varied etiologies, clinical presentations, diagnostic approaches, and management strategies.
  • To differentiate between acute and chronic salivary gland conditions and outline appropriate therapeutic interventions.

Main Methods:

  • Review of common salivary gland disorders, including acute suppurative sialadenitis, viral infections (mumps, HIV), recurrent parotitis, sialolithiasis, and tumors.

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  • Discussion of diagnostic modalities such as imaging (ultrasonography, CT, MRI) and biopsy (fine-needle aspiration).

    • Main Results:

    • Acute suppurative sialadenitis requires antibiotics, massage, hydration, and sialagogues.
    • Viral etiologies necessitate treatment of the primary infection.
    • Inflammatory conditions, often due to obstruction (stones, strictures), are managed by relieving the obstruction.
    • Salivary gland tumors, predominantly benign, are diagnosed via imaging and biopsy, with surgical excision as the primary treatment.

    Conclusions:

    • Effective management of salivary gland disorders hinges on accurate diagnosis of the underlying cause, whether infectious, inflammatory, or neoplastic.
    • Treatment strategies range from conservative measures for acute infections to surgical intervention for obstructive conditions and tumors.