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Heterochronic bilateral ectopic pregnancy after ovulation induction
Bo Zhu1, Gu-feng Xu, Yi-feng Liu
1Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China; Key Laboratory of Reproductive Genetics, Ministry of Education, Zhejiang University, Hangzhou 310006, China.
Journal of Zhejiang University. Science. B
|August 6, 2014
Summary
Assisted reproductive technologies (ART) like intrauterine insemination (IUI) can increase the risk of bilateral ectopic pregnancy. Clinicians must remain vigilant for a second ectopic pregnancy even after treating the first.
Area of Science:
- Reproductive Medicine
- Gynecology
- Obstetrics
Background:
- Assisted reproductive technologies (ART), including intrauterine insemination (IUI), are widely used but associated with an increased risk of ectopic pregnancy.
- Bilateral ectopic pregnancy, a rare complication, presents diagnostic challenges, particularly in pre-operative stages.
Observation:
- This paper details an unusual case of heterochronic bilateral ectopic pregnancy following stimulated IUI, with a 22-day interval between diagnoses.
- A literature review identified 16 reported cases of bilateral ectopic pregnancy since 2008, analyzing their characteristics.
Findings:
- Ovulation induction and other ARTs are significant risk factors for developing bilateral ectopic pregnancy.
- Ultrasonography often fails to identify bilateral ectopic pregnancy, complicating diagnosis and management.
Implications:
- Healthcare providers must maintain a high index of suspicion for a second ectopic pregnancy in patients undergoing treatment for the first.
- Intraoperative inspection of both fallopian tubes is crucial in all cases of suspected ectopic pregnancy to prevent missed diagnoses.
Keywords:
Assisted reproductive technologyHeterochronic bilateral ectopic pregnancyIntrauterine inseminationOvulation inductionMore Related Videos
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