IntergenicDB: a database for intergenic sequences

Daniel Luis Notari1, Aurione Molin2, Vanessa Davanzo2

  • 1Centro de Computação e Tecnologia da Informação, Universidade de Caxias do Sul, Rua Francisco Getúlio Vargas, 1130 - CEP 95070-560 - Caxias do Sul, Rio Grande do Sul, Brasil ; Instituto de Biotecnologia, Universidade de Caxias do Sul, Rua Francisco Getúlio Vargas, 1130 - CEP 95070-560 - Caxias do Sul, Rio Grande do Sul, Brasil.

Bioinformation
|August 7, 2014
PubMed
Summary

IntergenicDB provides a user-friendly database for bacterial intergenic regions, crucial for understanding gene regulation. This resource integrates gene information, simplifying access to non-coding DNA sequences.

Related Concept Videos

Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
45.9K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

3.0K
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
9.3K
Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
35.2K
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.3K
Organization of Genes02:07

Organization of Genes

Overview
64.7K