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Published on: July 14, 2023
Risk factors for stroke: a prospective hospital based study
Insights
Hypertension and diabetes are significant risk factors for both ischemic and hemorrhagic stroke. Identifying and managing these factors can help reduce the global burden of stroke.
Area of Science:
- Neurology
- Public Health
- Epidemiology
Background:
- Stroke is a leading cause of death globally.
- Identifying stroke risk factors is crucial for prevention and management.
- Acute stroke events contribute significantly to mortality.
Purpose of the Study:
- To identify significant risk factors associated with acute stroke.
- To investigate risk factors for both ischemic stroke (CI) and intra-cerebral hemorrhagic stroke (ICH).
Main Methods:
- Prospective study of 205 consecutive stroke patients.
- Included clinical evaluation, neurological assessment, laboratory tests, and brain CT.
- Follow-up at 14 days for all patients admitted within 48 hours of stroke onset.
Main Results:
- Ischemic stroke (CI) accounted for 76% of cases, and intra-cerebral hemorrhagic stroke (ICH) for 24%.
- Significant risk factors for all stroke types included hypertension, diabetes, and hypercholesterolemia.
- Age and age category were significant for stroke subtypes, with higher modified Rankin Scale (mRS) and lower Glasgow Coma Scale (GCS) scores indicating worse outcomes.
Conclusions:
- The study confirms the association between identified risk factors and acute stroke.
- Targeted interventions to mitigate these risk factors can substantially decrease the stroke burden.
Background:
The stroke is third leading cause of death in world and most patients die with an acute event in stroke. Various clinical variables have been investigated as risks factors of stroke. The study was aimed to identify these risks factors for stroke.
Methods:
This prospective study included 205 consecutive patients of stroke admitted in Combined Military Hospital/Sheik Khalifa Bin Zyad Hospital Muzaffarabad Azad Kashmir. The risk factors of stroke were investigated. Examination included clinical, neurological evaluation, laboratory tests, and brain CT. The follow-up at 14 days were done for all patients. Patients included were with acute first ever stroke onset of 48 hours of hospital admission. All patients completed a structured questionnaire and a physical examination and most provided blood for relevant investigations.
Results:
Two hundred and five cases stroke sub-types were (n = 156, 76%, with ischemic stroke (CI); n = 49, 24%, with intra-cerebral hemorrhagic stroke (ICH). The significant risk factors for all stroke were: Hypertension (p = 0.003), diabetes (p = < 0.001), Hypercholesterolemia (p = 0.686); atrial fibrillation (p = 0.445), cardiac diseases (p = 0.938). smoking (p = 0.926) for brain infarction and hypertension (p = 0.002), diabetes (p = < 0.001). Hypercholesterolemia (p = 0.018); atrial fibrillation (p = 0.449), cardiac diseases (p = 0.749), smoking (p = 0.829) for hemorrhagic stroke. Age significance (CI: p = 0.247 vs. ICH: p = 0.013) and age category significance were (CI: p = < 0.001 vs. ICH: p = 0.871) for subtype of stroke. High mRS (p < 0.001) low GCS score (p < 0.001) on admission were associated with worst outcome for both stroke subtype. These risk factors were all significant for CI as well as ICH.
Conclusions:
This study signifies the association of risks factors with acute stroke. Targeted interventions that reduce these risk factors could substantially reduce the burden of stroke
Related Concept Videos
Hemorrhagic Stroke l: Introduction
Ischemic Stroke l: Introduction
Hypertension III: Clinical Manifestations and Diagnostic Studies
Stroke: Introduction and Types
Coronary Artery Disease I: Introduction
Hemorrhagic Stroke ll: Pathophysiology
