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Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
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Remodeling cell surface glycans using glycosylation inhibitors

Norihito Kawasaki1

  • 1Food & Health Programme, Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK, norihito.kawasaki@ifr.ac.uk.

Methods in Molecular Biology (Clifton, N.J.)
|August 14, 2014
PubMed
Summary

This study presents a straightforward method for altering cell surface N-glycans in mammals. This technique uses enzyme inhibitors to modify glycosylation, impacting glycan-lectin interactions.

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