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Related Concept Videos

Cholecystitis01:20

Cholecystitis

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Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
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Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

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Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
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Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

1.5K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.5K
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

1.2K
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
1.2K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

903
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
903
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

24
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80%...
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The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
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Acute cholecystitis.

Valerie Halpin1

  • 1Legacy Good Samaritan Hospital, Portland, OR, US.

BMJ Clinical Evidence
|August 22, 2014
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates treatments for acute cholecystitis, a common condition often caused by gallstones. It analyzes interventions like early or laparoscopic cholecystectomy versus observation for optimal patient outcomes.

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Evidence-Based Medicine

Background:

  • Acute cholecystitis affects 20% of patients hospitalized for biliary tract disease.
  • Gallstones are present in approximately 95% of acute cholecystitis cases.
  • Optimal treatment timing and approach for acute cholecystitis remain debated.

Purpose of the Study:

  • To systematically review the effects of various treatments for acute cholecystitis.
  • To answer the clinical question regarding the efficacy and safety of different therapeutic interventions.

Main Methods:

  • A systematic review of medical literature was conducted, searching databases like Medline, Embase, and The Cochrane Library up to October 2013.
  • Included studies were evaluated using the GRADE system for evidence quality.
  • Harms alerts from regulatory agencies (FDA, MHRA) were also incorporated.

Main Results:

  • Eighteen studies met the inclusion criteria for the systematic review.
  • The review focused on evaluating interventions for acute cholecystitis based on GRADE criteria.

Conclusions:

  • The systematic review presents findings on the effectiveness and safety of key interventions for acute cholecystitis.
  • Interventions evaluated include early cholecystectomy, laparoscopic cholecystectomy, open cholecystectomy, percutaneous cholecystostomy, and observation alone.