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Updated: Apr 25, 2026

Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
[Soft tissue tumor near the joint: hibernoma]
J Schmolders1, S Gravius1, M J Friedrich1
1Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn.
Abstract:
Joint associated tumors must undergo histological analysis, since not only inflammatory, but also benign and malign tumors exist in this location. We report a well circumscribed tumor, located in the elbow that histologically turned out to be a hibernoma. Complete surgical excision is the therapy of choice and recurrences are rare. To rule out liposarcoma with hibernoma like changes, fluorescence in-situ hybridisation has been performed and showed no MDM-2 amplification. Hibernomas are tumors of brown adipose tissue that may be localized next to joints.
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