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Circulating miR-1, miR-133a, and miR-206 levels are increased after a half-marathon run
Clarissa P C Gomes1, Getúlio P Oliveira, Bibiano Madrid
1Pós-Graduação em Ciências Genômicas e Biotecnologia, Universidade Católica de Brasília , Brasília, DF , Brazil .
Context:
Circulating miRNAs are potential biomarkers that can be important molecules driving cell-to-cell communication.
Objective:
To investigate circulating muscle-specific miRNAs in recreational athletes.
Materials And Methods:
Three miRNAs from whole plasma before and after a half-marathon were analyzed by qPCR.
Results:
MiR-1, -133a, and -206 significantly increased after the race.
Discussion:
Increased levels of miRNAs after exercise point to potential biomarkers and to the possibility of being functional players following endurance training.
Conclusion:
These miRNAs are potential biomarkers of muscle damage or adaptation to exercise.
